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1

Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1

Keiro Shirotani, Dieter Edbauer, Marcus Kostka, Harald Steiner, Christian Haass

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

2

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

Dormann, Dorothee, Rodde, Ramona, Edbauer, Dieter, Bentmann, Eva, Fischer, Ingeborg, Hruscha, Alexander, Than, Manuel E, Mackenzie, Ian R A, Capell, Anja, Schmid, Bettina

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 2.60 MB

english, 2010

3

Reconstitution of γ-secretase activity

Edbauer, Dieter, Winkler, Edith, Regula, Joerg T., Pesold, Brigitte, Steiner, Harald, Haass, Christian

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 235 KB

english, 2003

4

The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity

Kaether, Christoph, Capell, Anja, Edbauer, Dieter, Winkler, Edith, Novak, Bozidar, Steiner, Harald, Haass, Christian

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 390 KB

english, 2004

5

Role of Septin Cytoskeleton in Spine Morphogenesis and Dendrite Development in Neurons

Tomoko Tada, Alyson Simonetta, Matthew Batterton, Makoto Kinoshita, Dieter Edbauer, Morgan Sheng

Journal:

Current Biology

Year:

2007

Language:

english

File:

PDF, 1.07 MB

english, 2007

6

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

Dieter Edbauer, Joel R. Neilson, Kelly A. Foster, Chi-Fong Wang, Daniel P. Seeburg, Matthew N. Batterton, Tomoko Tada, Bridget M. Dolan, Phillip A. Sharp, Morgan Sheng

Journal:

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

7

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

Dieter Edbauer, Joel R. Neilson, Kelly A. Foster, Chi-Fong Wang, Daniel P. Seeburg, Matthew N. Batterton, Tomoko Tada, Bridget M. Dolan, Phillip A. Sharp, Morgan Sheng

Journal:

Year:

2010

Language:

english

File:

PDF, 230 KB

english, 2010

8

O4-04-06 β-Amyloid precursor protein intracellular domain (AICD) strongly enhances resting free cytosolic calcium levels

Runa Hamid, Michael Willem, Dieter Edbauer, Harald Steiner, Ulrike Müller, Gerda Wünsch, Hans Kretzschmar, Christian Haass, Jochen Herms

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

9

miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

Mellios, Nikolaos, Sugihara, Hiroki, Castro, Jorge, Banerjee, Abhishek, Le, Chuong, Kumar, Arooshi, Crawford, Benjamin, Strathmann, Julia, Tropea, Daniela, Levine, Stuart S, Edbauer, Dieter, Sur, Mrig

Journal:

Nature Neuroscience

Year:

2011

Language:

english

File:

PDF, 632 KB

english, 2011

10

hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients withC9orf72mutations

Mori, Kohji, Lammich, Sven, Mackenzie, Ian R. A., FornÃ©, Ignasi, Zilow, Sonja, Kretzschmar, Hans, Edbauer, Dieter, Janssens, Jonathan, Kleinberger, Gernot, Cruts, Marc, Herms, Jochen, Neumann, Manuel

Journal:

Acta Neuropathologica

Year:

2013

Language:

english

File:

PDF, 933 KB

english, 2013

11

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

Orozco, Denise, Tahirovic, Sabina, Rentzsch, Kristin, Schwenk, Benjamin M, Haass, Christian, Edbauer, Dieter

Journal:

Year:

2012

Language:

english

File:

PDF, 398 KB

english, 2012

12

Staufen2 Regulates Neuronal Target RNAs

Heraud-Farlow, Jacki E., Sharangdhar, Tejaswini, Li, Xiao, Pfeifer, Philipp, Tauber, Stefanie, Orozco, Denise, Hörmann, Alexandra, Thomas, Sabine, Bakosova, Anetta, Farlow, Ashley R., Edbauer, Dieter,

Journal:

Year:

2013

Language:

english

File:

PDF, 1.65 MB

english, 2013

13

Early dipeptide repeat pathology in a frontotemporal dementia kindred withC9ORF72mutation and intellectual disability

Proudfoot, Malcolm, Gutowski, Nick J., Edbauer, Dieter, Hilton, David A., Stephens, Mark, Rankin, Julia, Mackenzie, Ian R. A.

Journal:

Acta Neuropathologica

Year:

2014

Language:

english

File:

PDF, 490 KB

english, 2014

14

FUS-mediated alternative splicing in the nervous system: consequences for ALS and FTLD

Orozco, Denise, Edbauer, Dieter

Journal:

Journal of Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 382 KB

english, 2013

15

P4-192 Structure-function analysis of the gamma-secretase complex subunit PEN-2

Steiner, Harald, Prokop, Stefan, Shirotani, Keiro, Edbauer, Dieter, Winkler, Edith, Haass, Christian

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 168 KB

english, 2004

16

Familial Als-associated Fused in Sarcoma (fus) Mutations Disrupt Transportin-mediated Nuclear Import

Haass, Christian, Rodde, Ramona, Edbauer, Dieter, Bentmann, Eva, Fischer, Ingeborg, Hruscha, Alexander, Than, Manuel, Mackenzie, Ian, Capell, Anja, Schmid, Bettina, Neumann, Manuela, Dormann, Dorothee

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 135 KB

english, 2010

17

Good guy or bad guy: the opposing roles of microRNA 125b in cancer

Banzhaf-Strathmann, Julia, Edbauer, Dieter

Journal:

Cell Communication and Signaling

Year:

2014

Language:

english

File:

PDF, 584 KB

english, 2014

18

microRNA-34c is a novel target to treat dementias

Zovoilis, Athanasios, Agbemenyah, Hope Y, Agis-Balboa, Roberto C, Stilling, Roman M, Edbauer, Dieter, Rao, Pooja, Farinelli, Laurent, Delalle, Ivana, Schmitt, Andrea, Falkai, Peter, Bahari-Javan, Sana

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.82 MB

english, 2011

19

Insulin-degrading Enzyme Rapidly Removes the β-Amyloid Precursor Protein Intracellular Domain (AICD)

Edbauer, Dieter, Willem, Michael, Lammich, Sven, Steiner, Harald, Haass, Christian

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 649 KB

english, 2002

20

RETRACTED ARTICLE: A new inducible transgenic mouse model for C9orf72-associated GGGGCC repeat expansion supports a gain-of-function mechanism in C9orf72-associated ALS and FTD

Hukema, Renate K, Riemslagh, Fréderike W, Melhem, Shamiram, van der Linde, Herma C, Severijnen, Lies-Anne, Edbauer, Dieter, Maas, Alex, Charlet-Berguerand, Nicolas, Willemsen, Rob, van Swieten, John C

Journal:

Acta Neuropathologica Communications

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

21

Distribution of dipeptide repeat proteins in cellular models andC9orf72mutation cases suggests link to transcriptional silencing

Schludi, Martin H., May, Stephanie, Grässer, Friedrich A., Rentzsch, Kristin, Kremmer, Elisabeth, Küpper, Clemens, Klopstock, Thomas, Arzberger, Thomas, Edbauer, Dieter

Journal:

Acta Neuropathologica

Year:

2015

Language:

english

File:

PDF, 2.11 MB

english, 2015

22

Erratum to: Distribution of dipeptide repeat proteins in cellular models andC9orf72mutation cases suggests link to transcriptional silencing

Schludi, Martin H., May, Stephanie, Grässer, Friedrich A., Rentzsch, Kristin, Kremmer, Elisabeth, Küpper, Clemens, Klopstock, Thomas, Arzberger, Thomas, Edbauer, Dieter

Journal:

Acta Neuropathologica

Year:

2015

Language:

english

File:

PDF, 512 KB

english, 2015

23

Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies inC9ORF72mutation carriers

Mackenzie, Ian R. A., Frick, Petra, Grässer, Friedrich A., Gendron, Tania F., Petrucelli, Leonard, Cashman, Neil R., Edbauer, Dieter, Kremmer, Elisabeth, Prudlo, Johannes, Troost, Dirk, Neumann, Manue

Journal:

Acta Neuropathologica

Year:

2015

Language:

english

File:

PDF, 1.65 MB

english, 2015

24

Three novelpresenilin 1mutations marking the wide spectrum of age at onset and clinical patterns in familial Alzheimer’s disease

Roeber, Sigrun, Müller-Sarnowski, Felix, Kress, Julia, Edbauer, Dieter, Kuhlmann, Tanja, Tüttelmann, Frank, Schindler, Christoph, Winter, Pia, Arzberger, Thomas, Müller, Ulrich, Danek, Adrian, Kretzsc

Journal:

Journal of Neural Transmission

Year:

2015

Language:

english

File:

PDF, 368 KB

english, 2015

25

Strategies to Generate Molecular and Cellular Tumor Vaccines for Low Grade Non-Hodgkin’s Lymphoma

Hallek, Michael, Buhmann, Raymund, Röhnisch, Tim, Wendtner, Clemens-Martin, Edbauer, Dieter, Emmerich, Bertold, Hiddemann, Wolfgang

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 10 KB

english, 2011

26

An amyloid-like cascade hypothesis for C9orf72 ALS/FTD

Edbauer, Dieter, Haass, Christian

Journal:

Current Opinion in Neurobiology

Year:

2016

Language:

english

File:

PDF, 855 KB

english, 2016

27

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS

Suárez-Calvet, Marc, Neumann, Manuela, Arzberger, Thomas, Abou-Ajram, Claudia, Funk, Eva, Hartmann, Hannelore, Edbauer, Dieter, Kremmer, Elisabeth, Göbl, Christoph, Resch, Moritz, Bourgeois, Benjamin,

Journal:

Acta Neuropathologica

Year:

2016

Language:

english

File:

PDF, 4.15 MB

english, 2016

28

Presenilin-1 Affects Trafficking and Processing of βAPP and Is Targeted in a Complex with Nicastrin to the Plasma Membrane

Christoph Kaether, Sven Lammich, Dieter Edbauer, Michaela Ertl, Jens Rietdorf, Anja Capell, Harald Steiner and Christian Haass

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 3.72 MB

english, 2002

29

Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide‐repeat protein deposition

Mori, Kohji, Nihei, Yoshihiro, Arzberger, Thomas, Zhou, Qihui, Mackenzie, Ian R, Hermann, Andreas, Hanisch, Frank, Kamp, Frits, Nuscher, Brigitte, Orozco, Denise, Edbauer, Dieter, Haass, Christian

Journal:

Year:

2016

Language:

english

File:

PDF, 2.96 MB

english, 2016

30

Retraction Note to: A new inducible transgenic mouse model for C9orf72-associated GGGGCC repeat expansion supports a gain-of-function mechanism in C9orf72-associated ALS and FTD

Hukema, Renate K., Riemslagh, Fréderike W., Melhem, Shamiram, van der Linde, Herma C., Severijnen, Lies-Anne W. F. M., Edbauer, Dieter, Maas, Alex, Charlet-Berguerand, Nicolas, Willemsen, Rob, van Swi

Journal:

Acta Neuropathologica Communications

Year:

2016

Language:

english

File:

PDF, 234 KB

english, 2016

31

Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD

Khosravi, Bahram, Hartmann, Hannelore, May, Stephanie, Möhl, Christoph, Ederle, Helena, Michaelsen, Meike, Schludi, Martin H., Dormann, Dorothee, Edbauer, Dieter

Journal:

Human Molecular Genetics

Year:

2016

Language:

english

File:

PDF, 2.00 MB

english, 2016

32

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model ofC9orf72associated neurodegeneration

Ohki, Yu, Wenninger-Weinzierl, Andrea, Hruscha, Alexander, Asakawa, Kazuhide, Kawakami, Koichi, Haass, Christian, Edbauer, Dieter, Schmid, Bettina

Journal:

Molecular Neurodegeneration

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

33

Targeting RNA G‐quadruplexes as new treatment strategy for C9orf72 ALS/FTD

Schludi, Martin H, Edbauer, Dieter

Journal:

EMBO Molecular Medicine

Year:

2017

Language:

english

File:

PDF, 281 KB

english, 2017

34

C9ORF72 TRANSLATION AND DISEASE

Edbauer, Dieter

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 423 KB

english, 2017

35

In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment

Guo, Qiang, Lehmer, Carina, Martínez-Sánchez, Antonio, Rudack, Till, Beck, Florian, Hartmann, Hannelore, Pérez-Berlanga, Manuela, Frottin, Frédéric, Hipp, Mark S., Hartl, F. Ulrich, Edbauer, Dieter, B

Journal:

Year:

2018

Language:

english

File:

PDF, 7.83 MB

english, 2018

36

RNA versus protein toxicity in C9orf72 ALS/FTLD

Arzberger, Thomas, Schludi, Martin H., Lehmer, Carina, Schmid, Bettina, Edbauer, Dieter

Journal:

Acta Neuropathologica

Year:

2018

Language:

english

File:

PDF, 886 KB

english, 2018

37

RNA-Dependent Intergenerational Inheritance of Enhanced Synaptic Plasticity after Environmental Enrichment

Benito, Eva, Kerimoglu, Cemil, Ramachandran, Binu, Pena-Centeno, Tonatiuh, Jain, Gaurav, Stilling, Roman Manuel, Islam, Md Rezaul, Capece, Vincenzo, Zhou, Qihui, Edbauer, Dieter, Dean, Camin, Fischer,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.86 MB

english, 2018

38

Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers

Frick, Petra, Sellier, Chantal, Mackenzie, Ian R. A., Cheng, Chieh-Yu, Tahraoui-Bories, Julie, Martinat, Cecile, Pasterkamp, R. Jeroen, Prudlo, Johannes, Edbauer, Dieter, Oulad-Abdelghani, Mustapha, F

Journal:

Acta Neuropathologica Communications

Year:

2018

Language:

english

File:

PDF, 3.23 MB

english, 2018